Symbiosis Pharmaceutical Services

Symbiosis Pharmaceutical Services is a UK-based CDMO and laboratory services provider focused on sterile drug products, including biologics, small molecules and viral-vector products. Its portfolio combines GMP manufacturing, in-house QC testing, lyophilisation and clinical packaging.

Sterile Drug-Product Manufacturing

• Manufacture sterile injectable drug products for clinical and commercial use through GMP aseptic fill-finish of liquid and lyophilised biological and small-molecule products.
• Fill client products into vials at clinical and low-volume commercial scale, including viral-vector drug products with BSL-2 capability. Typical vial sizes range from 2 mL to 100 mL, with batch sizes from 100 to 15,000 vials.
• Add lyophilisation within GMP aseptic filling processes, using independent lyophilisers for bulk batches up to 100 litres and cycles up to and beyond 72 hours.

Formulation, Testing and Release

• Develop pharmaceutical formulations during preclinical and manufacturing-development stages, either directly or with support from trusted expert providers.
• Test drug products through an in-house QC laboratory, covering raw materials, in-process controls, final product release and stability. Testing includes analytical and microbiological methods such as HPLC, bioburden and endotoxin.
• Support product quality decisions with sterility assurance and microbiology testing, including bioburden and endotoxin testing within client manufacturing projects.

Clinical Packaging and Labelling

• Prepare drug products for clinical trials and niche commercial markets through in-house labelling and packaging in dedicated suites, including open-label and non-clinical packaging.
• Apply product labels manually or automatically with QA oversight, and provide QA and QP review and certification for packaged clinical materials. Finished product is stored under controlled temperature and humidity before dispatch, as part of its projects.

Integrated CDMO Delivery

• Coordinate fill-finish manufacturing with analytical testing, QC inspection, labelling and packaging, QP release, and temperature-controlled storage within an integrated CDMO service.
• Take complex drug products from fill-finish through QP release, including small molecules, biologics, cytotoxic products and viral-vector products.

Best Fit

• Best suited to therapy developers and pharmaceutical teams needing GMP sterile drug-product manufacture, vial fill-finish or lyophilisation for clinical or low-volume commercial supply.
• Also fits sponsors seeking integrated QC, stability, packaging and release activities or in-house clinical labelling and packaging for open-label and other clinical studies.