Medicinal Chemistry, Hit-to-Lead & Lead Optimization Vendors
Medicinal chemistry and the optimization of hits and lead series into development candidates, including structure-activity relationship (SAR) work, analog design and synthesis, and iterative design-make-test-analyze cycles.
Related workflows
CRO / Research Services Provider · +5 more types
Frontage Laboratories is a CRO and CDMO providing bioanalysis, DMPK and ADME studies, toxicology, Phase I support, and drug manufacturing.
Evidence-backed capability match
“Our compound screen and lead generation (Hit-to-Lead), lead optimization, process chemistry and manufacturing, and customer synthesis enables speedy advancement of drugs from labs…”Source: frontagelab.com
Also offers: Bioanalysis & Biomarker Assay Services, Integrated CDMO/CMO Services, +3 more
CRO / Research Services Provider · +4 more types
Champions Oncology is an oncology CRO providing preclinical efficacy models, PDX studies, and clinical trial bioanalytical and biomarker testing.
Products: TumorGraft, TumorGraft3D +5 more
Evidence-backed capability match
“Prioritize chemotype selection and conduct SAR for challenging targets within an intracellular setting, ensuring authentic target binding despite complexities such as cellular…”Source: championsoncology.com
Also offers: In Vivo Pharmacology & Efficacy Models, Oncology Models & PDX Studies, +1 more
Compare listed vendors
| Vendor | Delivery model | In their words |
|---|---|---|
| Champions Oncology | CRO / Research Services Provider | “Prioritize chemotype selection and conduct SAR for challenging targets within an intracellular setting, ensuring authentic target binding despite complexities…”championsoncology.com · reviewed Oct 14, 2026 |
| Frontage Laboratories | CRO / Research Services Provider | “Our compound screen and lead generation (Hit-to-Lead), lead optimization, process chemistry and manufacturing, and customer synthesis enables speedy…”frontagelab.com · reviewed Oct 21, 2026 |