Disease Biology & Mechanism-of-Action Studies Vendors
Experimental biology services that characterize disease pathways, cellular mechanisms, pharmacology, and mechanism of action for discovery-stage programs.
Related workflows
Product / Instrument Supplier · +4 more types
BioIVT supplies human and animal biospecimens, hepatocytes, PBMCs and other primary cells, plus ADME, DDI, bioanalysis and in vitro assay services.
Evidence-backed capability match
“Understand mechanism of action of compounds”Source: bioivt.com
Also offers: Cell Culture, Cell Models & Organoid Products, Human Biospecimens & Biobank Samples, +2 more
CRO / Research Services Provider · +5 more types
Frontage Laboratories is a CRO and CDMO providing bioanalysis, DMPK and ADME studies, toxicology, Phase I support, and drug manufacturing.
Evidence-backed capability match
“We have established more than a dozen FACS assays for the Jak/Tyk2-Stat pathway to dissect the effects of various cytokines and individual Jak/Tyk2 kinases using human PBMC.”Source: frontagelab.com
Also offers: Bioanalysis & Biomarker Assay Services, Integrated CDMO/CMO Services, +3 more
CRO / Research Services Provider · +5 more types
Inotiv is a CRO and research models provider offering toxicology, in vivo pharmacology, research and transgenic models, bioanalysis and DMPK.
Products: Teklad, Target Sufficiency +1 more
Evidence-backed capability match
“Safety assessment, efficacy, and mode-of-action studies to support regulatory requirements, pre-clinical safety, and investigative toxicology.”Source: inotiv.com
Also offers: Toxicology Studies, In Vivo Pharmacology & Efficacy Models, +3 more
CRO / Research Services Provider · +4 more types
Crown Bioscience is a translational oncology CRO offering in vivo efficacy studies, PDX and cancer models, biomarker discovery, and clinical biomarker testing.
Products: OrganoidXplore, HuGEMM +3 more
Evidence-backed capability match
“Characterize drug-target interactions and confirm the Mechanism of Action (MoA) for your therapeutic candidate through integrated in vitro and in vivo studies.”Source: crownbio.com
Also offers: In Vivo Pharmacology & Efficacy Models, Oncology Models & PDX Studies, +2 more
CRO / Research Services Provider · +4 more types
Champions Oncology is an oncology CRO providing preclinical efficacy models, PDX studies, and clinical trial bioanalytical and biomarker testing.
Products: TumorGraft, TumorGraft3D +5 more
Evidence-backed capability match
“Accelerate drug development by identifying new therapeutic targets and studying mechanisms of action”Source: championsoncology.com
Also offers: In Vivo Pharmacology & Efficacy Models, Oncology Models & PDX Studies, +1 more
Compare listed vendors
| Vendor | Delivery model | Also offers | In their words |
|---|---|---|---|
| BioIVT | Product / Instrument Supplier | — | “Understand mechanism of action of compounds”bioivt.com · reviewed Oct 26, 2026 |
| Champions Oncology | CRO / Research Services Provider | Target Identification & Validation | “Accelerate drug development by identifying new therapeutic targets and studying mechanisms of action”championsoncology.com · reviewed Oct 21, 2026 |
| Crown Bioscience | CRO / Research Services Provider | Integrated Drug Discovery CRO Services, Target Identification & Validation | “Characterize drug-target interactions and confirm the Mechanism of Action (MoA) for your therapeutic candidate through integrated in vitro and in vivo studies.”crownbio.com · reviewed Oct 21, 2026 |
| Frontage Laboratories | CRO / Research Services Provider | Integrated Drug Discovery CRO Services | “We have established more than a dozen FACS assays for the Jak/Tyk2-Stat pathway to dissect the effects of various cytokines and individual Jak/Tyk2 kinases…”frontagelab.com · reviewed Oct 21, 2026 |
| Inotiv | CRO / Research Services Provider | — | “Safety assessment, efficacy, and mode-of-action studies to support regulatory requirements, pre-clinical safety, and investigative toxicology.”inotiv.com · reviewed Oct 21, 2026 |