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Preclinical & Translational DevelopmentPreclinical Development & IND-Enabling

DMPK, ADME & Preclinical PK

Compare vendors for dmpk, adme & preclinical pk within Preclinical Development & IND-Enabling, covering Drug Metabolism, Pharmacokinetics & ADME Studies, In Vitro ADME, CYP & Metabolism Assays, Drug-Drug Interaction & Transporter Studies, Pharmacokinetics & PK/PD Modeling.

Capabilities in this workflow

Drug Metabolism, Pharmacokinetics & ADME StudiesIn Vitro ADME, CYP & Metabolism AssaysDrug-Drug Interaction & Transporter StudiesPharmacokinetics & PK/PD Modeling

Vendors supporting this workflow

Favicon of Frontage Laboratories

Frontage Laboratories

CRO / Research Services Provider · +5 more types

Frontage Laboratories is a CRO and CDMO providing bioanalysis, DMPK and ADME studies, toxicology, Phase I support, and drug manufacturing.
Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches Drug Metabolism, Pharmacokinetics & ADME Studies
“We offer extensive drug metabolism and pharmacokinetic capabilities for new chemical entities and compounds in development.”
Source: frontagelab.com

Also offers: Bioanalysis & Biomarker Assay Services, Integrated CDMO/CMO Services, +2 more

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Favicon of Inotiv

Inotiv

CRO / Research Services Provider · +5 more types

Inotiv is a CRO and research models provider offering toxicology, in vivo pharmacology, research and transgenic models, bioanalysis and DMPK.

Products: Teklad, Target Sufficiency +1 more

Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches Drug Metabolism, Pharmacokinetics & ADME Studies
“Inotiv's collaborative drug metabolism and DDI study de-risks small molecule candidates by translating advanced assays (like CYP inhibition and targeted proteomics) into…”
Source: inotiv.com

Also offers: Toxicology Studies, In Vivo Pharmacology & Efficacy Models, +3 more

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Favicon of Altasciences

Altasciences

CRO / Research Services Provider · +3 more types

Altasciences is an early phase CRO and CDMO providing toxicology, IND-enabling studies, clinical pharmacology, bioanalysis, and drug manufacturing.

Products: Acceleration Platform

Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches Drug Metabolism, Pharmacokinetics & ADME Studies
“Using a broad range of in vivo animal models, we conduct pharmacokinetic and pharmacodynamic (PK/PD) studies that deliver critical insights into your drug’s absorption…”
Source: altasciences.com

Also offers: Toxicology Studies, First-in-Human (Phase I) Clinical Pharmacology Support, +2 more

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Favicon of Crown Bioscience

Crown Bioscience

CRO / Research Services Provider · +4 more types

Crown Bioscience is a translational oncology CRO offering in vivo efficacy studies, PDX and cancer models, biomarker discovery, and clinical biomarker testing.

Products: OrganoidXplore, HuGEMM +3 more

Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches Drug Metabolism, Pharmacokinetics & ADME Studies
“We provide a one-stop and innovative DMPKT service for small molecule, therapeutic antibody, ADC as well as novel drug modalities from early discovery to IND submission during…”
Source: crownbio.com

Also offers: In Vivo Pharmacology & Efficacy Models, Oncology Models & PDX Studies, +2 more

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Favicon of Champions Oncology

Champions Oncology

CRO / Research Services Provider · +4 more types

Champions Oncology is an oncology CRO providing preclinical efficacy models, PDX studies, and clinical trial bioanalytical and biomarker testing.

Products: TumorGraft, TumorGraft3D +5 more

Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches Drug Metabolism, Pharmacokinetics & ADME Studies
“Pharmacokinetics & Drug Distribution -Analyzes how anti-cancer drugs distribute, metabolize, and clear within the body, and also helps optimize dosing and therapeutic windows.”
Source: championsoncology.com

Also offers: In Vivo Pharmacology & Efficacy Models, Oncology Models & PDX Studies, +1 more

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Favicon of BioIVT

BioIVT

Product / Instrument Supplier · +4 more types

BioIVT supplies human and animal biospecimens, hepatocytes, PBMCs and other primary cells, plus ADME, DDI, bioanalysis and in vitro assay services.
Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches Drug Metabolism, Pharmacokinetics & ADME Studies
“ADME, DMPK, and DDI studies including CYP inhibition, metabolic stability & transporters.”
Source: bioivt.com

Also offers: Cell Culture, Cell Models & Organoid Products, Human Biospecimens & Biobank Samples, +1 more

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Favicon of Celerion

Celerion

CRO / Research Services Provider · +2 more types

Celerion is a CRO and laboratory services provider supporting clinical development, bioanalysis, biometrics, trial operations, and regulatory submissions.

Products: ClinQuick

Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches In Vitro ADME, CYP & Metabolism Assays
“In vitro cross-species metabolism and metabolite identification using hepatocytes, liver microsomes, and S9 fractions”
Source: celerion.com

Also offers: First-in-Human (Phase I) Clinical Pharmacology Support, Clinical Trial Bioanalytical & Biomarker Testing, +2 more

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Favicon of Simulations Plus

Simulations Plus

Software / Technology Platform · +4 more types

Simulations Plus is a drug-development software and consulting provider offering PBPK modeling, pharmacometrics and QSP, and AI-driven drug design.

Products: GastroPlus, MonolixSuite +9 more

Evidence-backed workflow match
DMPK, ADME & Preclinical PK
Matches Pharmacokinetics & PK/PD Modeling
“Preclinical pharmacokinetics (PK) and Toxicokinetics (TK)”
Source: simulations-plus.com

Also offers: Model-Informed Drug Development (MIDD), PBPK Modeling, +3 more

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