Preclinical Development & IND-Enabling Vendors

“…research models combined with drug efficacy, pharmacology, and safety studies. Our experienced team of scientists has the expertise to offer a wide range of study designs in…”

“We offer extensive drug metabolism and pharmacokinetic capabilities for new chemical entities and compounds in development.”

“Our bioanalytical laboratories support LC MS/MS and ligand binding assays for small and large molecule programs.”

“Crown Bioscience offers a diverse range of efficacy models spanning in vitro, ex vivo, and in vivo systems.”

“Champions' in vivo testing solutions include a range of preclinical models and services for the preclinical assessment of novel anticancer agents across all therapeutic…”

“ADME, DMPK, and DDI studies including CYP inhibition, metabolic stability & transporters.”

“Streamlined, one-stop workflow from vector design to downstream functional assays.”

“In vitro cross-species metabolism and metabolite identification using hepatocytes, liver microsomes, and S9 fractions”

“To gain deeper insight into functional effects of a candidate drug, we offer robust cell-based screening services. Cell-based assays help bridge the gap between in vitro and in…”

“IND-enabling study design and GLP oversight”

“…We are able to develop and validate custom cell-based assays for research and development or perform analyses by routine procedures.”

“Preclinical pharmacokinetics (PK) and Toxicokinetics (TK)”